ADVANTAGES OF VAC POSTOPERATIVE ABDOMINAL WALL WOUND COMPLICATIONS TREATMENT IN CANCER PATIENTS

V. M. Lykhman, R. V. Ketsman, O. M. Postolov, V. Y. Chemadura, D. Ievtushenko, A. E. Osokin, T. Levenets, O. S. Suprun, K. S. Bogodenko
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Abstract

Summary. Introduction. Postoperative abdominal wall wound infevtions became significant problem om modern surgery impacting approximatly 110,800 patients in 2015. Aim of study. Comparison of postoperative abdominal wall wound complications treatment methods in cancer patients. Materials and method. 24 cases of patients with purulent-septic complications of postoperative wounds were analised. 10 (41,6 %) — men and 14 (58,4 %) — women. The average age of patients was 63,8±17,1 years. Patients were divided into two groups: a comparative group — 12 patients (routine treatment), and an experimental group — 12 patients, which was treated using the VAC system. Both groups received infusion and antibacterial therapy. Research results. In cultures of wound contents, the following were found: (1) Staphylococcus aureus — 38,9 %, (2) Staphylococcus epidermidis — 19,5 %, (3) Enterococcus faecalis — 19,1 %, (4) Escherichia coli — 15,4 %, (5) Pseudomonas aeruginosa — 5,8 %, (6) Proteus vulgaris — 0,9 %, as well as (7) gram-positive aerobic and facultatively anaerobic pathogens — 0,4 %. According to the results of bacteriological examination of the wound contents in the patients of the experimental group, the microbial count decreased statistically significantly (to 105-106, p>0,05) starting from the third day of treatment. In the comparative group — all indicators remained at the previous levels (108-109). Conclusions. VAC-therapy appeared superior in postoperative abdominal wall wound complications treatment in cancer patients. VAC significantly reduces both duration of hospital stay and mortality.
肿瘤患者术后腹壁创面并发症的治疗优势
总结。介绍。术后腹壁伤口感染成为现代外科手术的重要问题,2015年影响了约110,800例患者。研究目的。肿瘤患者术后腹壁创面并发症的治疗方法比较。材料和方法。对24例伤口术后脓毒性并发症进行分析。男性10人(41.6%),女性14人(58.4%)。患者平均年龄63.8±17.1岁。患者分为两组:对照组12例(常规治疗),实验组12例(使用VAC系统治疗)。两组均给予输液及抗菌治疗。研究的结果。在伤口内容物的培养中,发现如下:(1)金黄色葡萄球菌- 38.9%,(2)表皮葡萄球菌- 19.5%,(3)粪肠球菌- 19.1%,(4)大肠杆菌- 15.4%,(5)铜绿假单胞菌- 5.8%,(6)普通变形杆菌- 0.9%,以及(7)革兰氏阳性好氧和兼性厌氧病原体- 0.4%。实验组患者创面内容物细菌学检查结果显示,从治疗第3天开始,微生物数量显著下降(0.05 ~ 0.05,p < 0.05)。在比较组中,所有指标保持在以前的水平(108-109)。结论。在肿瘤患者术后腹壁创面并发症的治疗中,vaca疗法表现出优越性。VAC显著缩短了住院时间和死亡率。
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