Construction of Cardiovascular System Experimental Simulation Platform and Research on Flow Change

Gen Li, H. Cheng, Jie Hou, Dongfang Ding, Liuchuang Wei
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引用次数: 1

Abstract

The traditional Windkessel model cannot well explain how only a 1W multi-power heart overcomes various obstructions and viscous dissipation of the circulatory system, and smoothly transmits energy to the whole body. A closed-loop pressure system was built according to the cardiovascular structure. The experiments were carried out by changing the system pressure, the speed of the peristaltic pump and the stretch ratio of the experimental tube. The following conclusions were reached: 1. when the system pressure was 100mmHg, the speedwas70rad/min and the stretch ratiowas1.4, the maximum cumulative flow rate of 20min was 4991.7mL. 2. The average flow rate was positively correlated with the inner pipe pulse pressure (pulse pressure, PP), negatively correlated with the average pressure in the tube, and had no obvious relationship with the average pressure of inlet-outlet. 3. The inner pipe PP increased with the increase of circumferential elastic modulus of the experimental tube.
心血管系统实验仿真平台构建及血流变化研究
传统的Windkessel模型不能很好地解释只有1W的多功率心脏如何克服循环系统的各种障碍和粘性耗散,并顺利地将能量传递到全身。根据心血管结构,建立了闭环压力系统。通过改变系统压力、蠕动泵转速和实验管的拉伸比来进行实验。研究得出以下结论:1。当系统压力为100mmHg,速度为70rad/min,拉伸比为1.4时,20min最大累计流量为4991.7mL。2. 平均流量与管内脉冲压力(脉冲压力,PP)呈正相关,与管内平均压力呈负相关,与进出口平均压力无明显关系。3.管内PP随实验管周向弹性模量的增大而增大。
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