A Case of Mycosis Fungoides Developed Early After Hodgkin Lymphoma Treatment

Abstract

Coexistence or sequentially of Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) can occur in the same patient rarely. Although the underlying etiopathogenesis of this condition is not known for certain, reasons such as drugs, genetic and environmental factors, and the effect of the primary tumor are blamed. Also, synchronous or metachronous formation of HL and T-cell NHL in the same patient is known, and this occurs most often with mycosis fungoides (MF). MF usually precedes HL, but to a much lesser extent, the opposite is observed. There are often years between the development of two separate diseases. A 38-year-old male presented swelling on the neck, high fevers, sweating, and weight loss. A patient diagnosed with stage 4B HL-nodular sclerosis type after evaluation. ABVD regimen was initiated for the patient and 6 cycles of chemotherapy were completed. Complete response was observed after six cycles of chemotherapy. He did well for the next 2 months but then developed cutaneous lesions like slightly hypopigmented and dandruff patches on the trunk and MF diagnosed after skin biopsy. In HL patients, secondary malignancies such as MF may occur very soon after the end of treatment.