Lei Lin, Beilei Xu, Wencheng Wu, Trevor W. Richardson, Edgar A. Bernal, Bill Martens, C. Thornton, C. Heatwole
{"title":"Deep Metric Learning with Triplet Networks: Application to Hand-grip Myotonia Quantification","authors":"Lei Lin, Beilei Xu, Wencheng Wu, Trevor W. Richardson, Edgar A. Bernal, Bill Martens, C. Thornton, C. Heatwole","doi":"10.1109/HI-POCT45284.2019.8962888","DOIUrl":null,"url":null,"abstract":"Myotonia, which refers to delayed muscle relaxation after contraction, is the main symptom of myotonic dystrophy patients. The relaxation time after a hand squeeze has been used as a biomarker for diagnostic purposes and in clinical trials to quantify the effectiveness of a treatment. Current processes that rely on handcrafted features tend to be sensitive to data acquisition noise and intra- and inter-patient variability. In this work, we develop a deep metric learning framework for analyzing the hand-grip time series based on triplet-networks. Experiments show that the learned embedding space can be used to quantify the symptoms, evaluate the effectiveness of treatments, and design new data collection protocols.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":"37 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/HI-POCT45284.2019.8962888","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Myotonia, which refers to delayed muscle relaxation after contraction, is the main symptom of myotonic dystrophy patients. The relaxation time after a hand squeeze has been used as a biomarker for diagnostic purposes and in clinical trials to quantify the effectiveness of a treatment. Current processes that rely on handcrafted features tend to be sensitive to data acquisition noise and intra- and inter-patient variability. In this work, we develop a deep metric learning framework for analyzing the hand-grip time series based on triplet-networks. Experiments show that the learned embedding space can be used to quantify the symptoms, evaluate the effectiveness of treatments, and design new data collection protocols.