[Diagnosis of rejection after pancreatic transplantation in the minipig model].

P Friess, H Lippert, P Müller, F Noack, A Modrejewski, T Benhidjeb, U Hanack, H J Schulz, W D Kranz, M Schöpke
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引用次数: 0

Abstract

An allogenic transplantation of the total-pancreas with duodenum was carried out in the minipig model. The oral duodenum was closed blindly and the aboral part was led out as a stoma. The portal vein of the transplant was anastomosed end-to-side in the inferior vena cava and the celiac artery of the transplant in the distal aorta. Investigations for early diagnosis of rejection were carried out in this model parallelly respectively one by one. CT/MRT, selective angiography, laboratory chemical parameters were unsuitable for early detection. The pancreatic succus cytology and nuclear medical investigations show reproducible changes caused by rejection before the blood-sugar level was increased.

[微型猪胰腺移植后排斥反应的诊断]。
在小型猪模型上进行了全胰十二指肠同种异体移植。盲闭口十二指肠,将口部引出造口。移植门静脉端侧吻合于下腔静脉,移植腹腔动脉端侧吻合于远端主动脉。排斥反应早期诊断的调查在该模型中依次并行进行。CT/MRT、选择性血管造影、实验室化学参数不适合早期发现。胰浆液细胞学和核医学检查显示,在血糖水平升高之前,排斥反应引起了可重复的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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