Gold Coated Photonic Crystal Fiber-Based Biosensor for Pathogenic Bacteria Detection

Emranul Haque, A. Noman, Md. Billal Hossain, N. H. Hai, Feroz Ahmed
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Abstract

It is critical to identify pathogens such as Vibrio Cholera, Escherichia Coli (E. coli), Bacillus Anthracis, and Enterococcus Faecalis, which cause infections in the blood, lungs, and other bodily parts. We present here a Surface Plasmon Resonance (SPR) biosensor-based Photonic Crystal Fiber (PCF) for the detection of pathogenic bacteria which pollute drinking water. The proposed sensor exhibits excellent performance characteristics, and it has the configuration of detecting analyte samples externally. The sensor is built with a basic square lattice of PCF, covered with a thin chemically stable gold layer. The sensor's performance is studied numerically using a finite element (FE)-based simulation tool, where the highest wavelength sensitivity is found to be 5161 nm/RIU for detecting Enterococcus Faecalis bacteria. Other critical parameters such as Signal to Noise Ratio, Detection Limit, and Sensor Length are also evaluated and presented for the proposed PCF biosensor
基于金涂层光子晶体光纤的病原菌检测生物传感器
识别霍乱弧菌、大肠杆菌、炭疽芽孢杆菌和粪肠球菌等病原体至关重要,这些病原体会导致血液、肺部和其他身体部位感染。本文提出了一种基于表面等离子体共振(SPR)生物传感器的光子晶体光纤(PCF),用于检测污染饮用水的致病菌。该传感器具有优异的性能特征,并具有外部检测分析物样品的配置。该传感器由PCF的基本方形晶格构成,上面覆盖着一层薄薄的化学稳定的金层。利用有限元模拟工具对传感器的性能进行了数值研究,检测粪肠球菌细菌的最高波长灵敏度为5161 nm/RIU。其他关键参数,如信噪比,检测限和传感器长度也被评估和提出的PCF生物传感器
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