Analisis Kestabilan Model Seak Pada Penyebaran Penyakit Filariasis

A. Wahyudin, R. Ratianingsih, N. Nacong
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Abstract

Filariasis or elephantiasis is a disease caused by infection of filarial worms. This research studies the spread model of elephantiasis disease that is influenced by the birth rate, the natural mortality rate, the transfer rate of susceptible exposed mosquito to the exposure due to the interaction between susceptible mosquito and infected human population, the transfer rate of exposed mosquito to the infected, the transfer rate of vulnerable human to the exposure human populations as a result of the mosquito and susceptible human intraction, the transfer rate of exposed human population to the infected human population, and the transfer rate of the infected human population to chronically human population. Filariasis disease spread model is built in form of Susceptible - Exposed - Acute - Kronic (Seak). The model is a nonlinear differential equations system of dependent variables that are the vulnerable, exposed, infected human populations, and chronic and vulnerable exposed, and infected mosquito population.  The  model  has  a  critical  point  namely   that represents the free-disease conditions and the critical point  that represents an endemic condition. The critical points is analyzed using the method of linearized stability and Routh Hurwitz criteria.  is the vertical point stable while   is unstable. The result indicates that the free- disease condition is settled, while the endemic will be left in a long time period. It could also be interpreted that the endemic have a chance be overcome.
丝虫病或象皮病是一种由丝虫病感染引起的疾病。本研究研究了象皮病的传播模型,该模型受以下因素的影响:出生率、自然死亡率、因易感蚊子与受感染人群相互作用而导致的易感暴露蚊子对暴露的传播率、暴露蚊子对受感染人群的传播率、由于蚊子与易感人群相互作用而导致的易感人群对暴露人群的传播率。暴露人群向感染人群的转移率,以及感染人群向慢性人群的转移率。以易感-暴露-急性-慢性(Seak)模式建立丝虫病传播模型。该模型是一个非线性微分方程组的因变量,即易感人群、暴露人群、受感染人群和慢性易感人群、暴露人群和受感染蚊子群体。该模型有一个表示无病状态的临界点和一个表示地方病状态的临界点。利用线性化稳定性和劳斯赫维茨准则分析了系统的临界点。是垂直点稳定,是不稳定。结果表明,无病状态已得到解决,地方病仍将长期存在。这也可以解释为这种流行病有可能被克服。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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