Lymphatic innervation.

Blood vessels Pub Date : 1990-01-01 DOI:10.1159/000158803
N G McHale
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引用次数: 26

Abstract

Bovine mesenteric lymphatic vessels have nerves in their walls which in response to field stimulation cause an increase in frequency of spontaneous lymphatic contractions and this could be blocked by alpha-antagonists. When vessels were loaded with [3H]-noradrenaline, 3H-efflux was increased in response to field stimulation and this was potentiated by alpha 2-antagonists and depressed by alpha 2-agonists. Electrical activity in these vessels consisted of a single action potential which preceded each contraction. Mean resting potential was -61 mV +/- 5.7 (SD). Stimulation of postsynaptic alpha-receptors caused a depolarization accompanied by a decrease in membrane conductance while beta-receptor stimulation had the opposite effect. Lymphatic noradrenergic nerves appear to have a role in the living animal since stimulation of the sympathetic chain in anaesthetized sheep increased popliteal efferent lymph flow and this could be blocked by alpha-adrenergic blockers.

淋巴神经支配。
牛肠系膜淋巴管的管壁有神经,当受到电场刺激时,淋巴管自发收缩的频率增加,这可以被α -拮抗剂阻断。当血管负荷[3H]-去甲肾上腺素时,3H外排在电场刺激下增加,并被α 2拮抗剂增强,被α 2激动剂抑制。这些血管的电活动由每次收缩前的单一动作电位组成。平均静息电位为-61 mV +/- 5.7 (SD)。刺激突触后α受体引起去极化,同时膜电导降低,而刺激β受体则产生相反的效果。淋巴去肾上腺素能神经似乎在活的动物中有作用,因为在麻醉的羊交感神经链的刺激增加了腘窝传出淋巴流,这可以被α -肾上腺素能阻滞剂阻断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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