Effectiveness of WHO Combination Treatment Regimen in The Management of Diarrhoea Among Under-Five Children Attending Primary Health Care Centres in Oyo State, Nigeria

Opeyemi Oyewumi Zaccheus, N. Okafor, J. Adegoke, R. Anokwuru
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Abstract

Diarrhoea is one of the childhood diseases that result to high mortality. Despite the World Health Organization (WHO) recommendation of the combination treatment regimen of oral rehydration salts (ORS) and zinc supplements for the management of this disease, it effectiveness in treating and preventing the reoccurrence of diarrhoea among the under-five children remains a serious concern. Therefore, the main objective of this study was to assess the effectiveness of WHO combination treatment regimen in the management of diarrhoea amongst under-five children attending Primary Health Care (PHC) centres in Oyo State. The study adopted quasi-experimental of one group Pretest-posttest design. Purposive sampling technique was used to recruit a total of 60 eligible participants on admission. The effectiveness of the combination treatment regimen was assessed based on the recovery rate of the participants at 24 hours, 2 weeks and 4 weeks post intervention using a standardized instrument of WHO observational check-list for assessing diarrhoeaic under-five children. Data analysis was done using both descriptive and inferential statistics. However, on admission (baseline), majority 52(86.7%) of the participants had moderate diarrhoea. After administering WHO-ORS plus Zinc supplements, 24 hours later, majority 51(85.0%) of the participants had no diarrhoea, two (2) weeks later, during home visiting, majority 56(93.3%) of the participants had no diarrhoea. After Four (4) weeks, significant improvement was also achieved as 57(95.0%) participants had no diarrhoea. It was concluded that the significant improvement in the diarrhoea status in 24 hours, 2 weeks and 4 weeks post intervention was an indication that the combination of WHO-ORS plus zinc suggest how highly efficacious the regimen is in the management of under-five diarrhoea. Hence, Health workers in the PHC should combine the therapy and not using only one in the management of under-five diarrhoea.
世卫组织联合治疗方案在尼日利亚奥约州初级卫生保健中心治疗五岁以下儿童腹泻方面的有效性
腹泻是导致高死亡率的儿童疾病之一。尽管世界卫生组织(世卫组织)建议将口服补液盐(ORS)和锌补充剂联合治疗方案用于治疗这种疾病,但它在治疗和预防五岁以下儿童腹泻复发方面的有效性仍然令人严重关切。因此,本研究的主要目的是评估世卫组织联合治疗方案在奥约州初级卫生保健中心治疗五岁以下儿童腹泻方面的有效性。本研究采用一组准实验前测后测设计。采用有目的抽样技术,在入组时共招募60名符合条件的参与者。根据参与者在干预后24小时、2周和4周的康复率,使用世卫组织评估五岁以下腹泻儿童的观察性检查清单的标准化工具,对联合治疗方案的有效性进行了评估。数据分析使用描述性和推断性统计。然而,在入院时(基线),大多数52名(86.7%)参与者有中度腹泻。在给予WHO-ORS加锌补充剂24小时后,大多数51名(85.0%)参与者没有腹泻,两(2)周后,家访期间,大多数56名(93.3%)参与者没有腹泻。四(4)周后,57(95.0%)参与者没有腹泻,显著改善。结论是,干预后24小时、2周和4周腹泻状况的显著改善表明,世卫组织口服补液补液加锌的组合表明该方案在治疗5岁以下腹泻方面是多么有效。因此,初级保健中心的卫生工作者在治疗五岁以下腹泻时应结合使用这两种疗法,而不是只使用一种。
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