Diagnosis of Alzheimer Diseases in Early Step Using SVM (Support Vector Machine)

Amira Ben Rabeh, F. Benzarti, H. Amiri
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引用次数: 34

Abstract

Alzheimer is a disease that affects the brain. It causes degeneration of nerve cells (neurons) and in particular cells involved in memory and intellectual functions. Early diagnosis of Alzheimer Diseases (AD) raises ethical questions, since there is, at present, no cure to offer to patients and medicines from therapeutic trials appear to slow the progression of the disease as moderate, accompanying side effects sometimes severe. In this context, analysis of medical images became, for clinical applications, an essential tool because it provides effective assistance both at diagnosis therapeutic follow-up. Computer Assisted Diagnostic systems (CAD) is one of the possible solutions to efficiently manage these images. In our work, we proposed an application to detect Alzheimer's diseases. For detecting the disease in early stage we used the three sections: frontal to extract the Hippocampus (H), Sagittal to analysis the Corpus Callosum (CC) and axial to work with the variation features of the Cortex(C). Our method of classification is based on Support Vector Machine (SVM). The proposed system yields a 90.66% accuracy in the early diagnosis of the AD.
支持向量机在老年痴呆症早期诊断中的应用
阿尔茨海默病是一种影响大脑的疾病。它会导致神经细胞(神经元)的退化,特别是与记忆和智力功能有关的细胞。阿尔茨海默病(AD)的早期诊断引发了伦理问题,因为目前还没有治愈方法可以提供给患者,治疗试验中的药物似乎可以减缓疾病的进展,但伴随的副作用有时很严重。在这种情况下,医学图像分析成为临床应用的重要工具,因为它在诊断和治疗随访方面提供了有效的帮助。计算机辅助诊断系统(CAD)是有效管理这些图像的可能解决方案之一。在我们的工作中,我们提出了一个检测阿尔茨海默病的应用。为了在早期发现疾病,我们使用了三个切片:额叶提取海马(H),矢状面分析胼胝体(CC),轴向分析皮层的变化特征(C)。我们的分类方法是基于支持向量机(SVM)。该系统对AD的早期诊断准确率为90.66%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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