EFFECTS OF THE METHANOLIC EXTRACT FROM AROEIRA LEAVES (SCHINUS TEREBINTHIFOLIUS RADDI) ON THE IN VITRO GROWTH OF CORYNEBACTERIUM PSEUDOTUBERCULOSIS

L. E. A. Rodrigues, C. Santos, André Santos
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引用次数: 1

Abstract

Plants produce molecules such as terpenes, lectins and alkaloids that exert anticarcinogenic, antimicrobial and anti-inflammatory activities. Corynebacterium pseudotuberculosis is the etiological agent of caseous lymphadenitis in goats and sheep. The prevalence of this infection is high in northeastern of Brazil. The present study evaluated the effects of a methanolic extract from the leaves of the aroeira plant ( Schinus terebinthifolius Raddi ) on the in vivo growth of virulent and attenuated strains of this bacillus. The extract was tested at concentrations of 2000, 1500, 1000, 500, 250, 100 and 10 µg/dL for 48 hours. The first four concentrations inhibited bacterial growth, producing halos of decreasing diameters. No antibacterial effect was found with the remaining concentrations. These results show that bacterial growth was inhibited by an extract of Schinus terebinthifolius Raddi at the aforementioned concentrations.
石竹叶甲醇提取物对假结核棒状杆菌体外生长的影响
植物产生萜类、凝集素和生物碱等分子,发挥抗癌、抗菌和抗炎作用。假结核棒状杆菌是山羊和绵羊干酪样淋巴结炎的病原。这种感染在巴西东北部的流行率很高。本研究评估了一种从石竹(Schinus terebinthifolius Raddi)叶子中提取的甲醇提取物对该芽孢杆菌强毒株和弱毒株在体内生长的影响。提取液在浓度为2000、1500、1000、500、250、100和10µg/dL的条件下测试48小时。前四种浓度抑制细菌生长,产生直径变小的光晕。其余浓度均无抑菌作用。这些结果表明,在上述浓度下,三叶草提取物可以抑制细菌的生长。
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