3D Shear Wave Absolute Vibro-Elastography System for Targeted Prostate Biopsy: Initial Results

2022 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2022-10-10 DOI:10.1109/IUS54386.2022.9958838

Tajwar Abrar Aleef, Qi Zeng, H. Moradi, S. Mohammed, T. Currant, M. Honarvar, R. Rohling, S. S. Mahdavi, S. Salcudean

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引用次数: 2

Abstract

Quantitative tissue stiffness characterization can aid in diagnosing prostate cancer (PCa). Shear wave absolute vibro-elastography (SWAVE) provides volumetric, multi-frequency shear wave imaging with external excitation. In this work, we present a first-of-a-kind 3D multi-frequency endo-rectal SWAVE system with probe-mounted exciter for prostate imaging. The system uses a SonixTouch Ultrasound (US) with minimum hardware addition- making it compatible with the current clinical workflow. The exciter is designed to be sterilizable and it attaches to the US transducer and is programmed with a function generator. Sector-wise sequencing is utilized to boost the effective framerate of the US and satisfy the Nyquist sampling rate for tissue motion tracking. We characterize the system with quality assurance elastography phantoms and human liver data of healthy subjects- comparing with 3D Magnetic Resonance Elastography (MRE). High correlations between SWAVE and MRE were obtained in both phantoms (99%) and liver (94%).

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用于前列腺靶向活检的三维剪切波绝对振动弹性成像系统：初步结果

组织硬度定量表征有助于诊断前列腺癌（PCa）。剪切波绝对振动弹性成像（SWAVE）通过外部激励提供容积、多频剪切波成像。在这项工作中，我们展示了一种首创的三维多频直肠内 SWAVE 系统，该系统带有用于前列腺成像的探针安装式激励器。该系统使用 SonixTouch 超声波（US），只需增加最少的硬件，即可与当前的临床工作流程兼容。激发器设计为可灭菌，可安装在 US 传感器上，并通过功能发生器进行编程。利用扇区排序来提高 US 的有效帧速率，并满足组织运动跟踪的奈奎斯特采样率。我们利用质量保证弹性成像模型和健康受试者的人体肝脏数据对该系统进行了鉴定，并与三维磁共振弹性成像（MRE）进行了比较。在模型（99%）和肝脏（94%）中，SWAVE 和 MRE 都获得了很高的相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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2022 IEEE International Ultrasonics Symposium (IUS)

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