Simulation study on laser induced bubble generation of liquid in lumen

Abstract

In intravascular laser ablation procedures, rapidly expanding bubbles can inflict mechanical damage on the vessel walls, thereby rendering the transient characteristics of laser-induced bubble formation and evolution within the vessels a significant research topic. The high-density energy of the laser produces tension in the liquid; when this tension amplitude exceeds the stability limit of the medium, the liquid undergoes a phase transition, resulting in bubble formation. In this study, we employed numerical simulation techniques to construct a simplified model of laser-induced cavitation, capturing the velocity, pressure, and phase distribution within the fluid region during bubble evolution. Additionally, we analyzed trends in bubble variation throughout its formation and evolution within the lumen environment. This research could facilitate preliminary prediction of vessel wall damage in laser ablation procedures and provide direction for improvement