Anterior cervical discectomy and fusion by polyetheretherketon cage in degenerative disc diseases

Bahaa El Serwi, Mahmoud Hadhood, Y. Allam, A. E. El Deen, O. Sherif
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Abstract

Background Anterior cervical discectomy has proven to be a safe and effective procedure for the treatment of degenerative disc disease. The anterior approach allows direct visualization of the entire interspace and wide decompression of the anterior aspect of cervical spinal cord and nerve roots; it may be undertaken in cases of multilevel disease and interbody fusion may be performed if required. Patients and methods A total of 20 patients aged from 20 to 65 years, 16 females and four males with symptomatic cervical disc disease, presented in the outpatient clinic, Menoufia University hospital from 2012 to 2014, were examined and followed up prospectively, The mean age was 43.25±9.06 (range: 28–60) years. There were 13 patients (65%) with radiculopathy only, two patients (10%) with mylopathy only, and five patients (10%) with radiculomylopathy; seven cases were affected by mylopathy graded according to Ranawat grading. There were 37 levels affected among the 20 patients. C5,6 was the commonly affected level 1 (40.5%), then C4,5 11 (29.7%), then C6,7 7 (18.9%), and the least one was C3,4 4 (10.8%). Five cases were operated by using a microscope. Anterior cervical discectomy and fusion (ACDF) were performed using polyetheretherketone (PEEK) cages and local bone graft. Results The mean operative time per microscopic level was 64.5 min, the nonmicroscopic level was 47 min.The only intraoperative complication was external jugular-vein ligation that occurred in two cases (nonmicroscopic). The only postoperative complication was difficulty in swallowing, which occurred in 13 cases (11 nonmicroscopic and two microscopic). The mean of preoperative interbody ratio was 1.8±0.2, 12 months postoperatively the mean was 1.9± 0.2.There was a statistically significant difference in the mean of the interbody ratio preoperative and at 12 months. The mean preoperative disc space height was 3.3±0.8 mm, 12 months postoperative was 5.8±0.9. There was a statistically significant difference in the mean disc space height preoperative and 12 months postoperative. Rate of fusion at 12 months: three levels were average fusion, 26 levels were good fusion, and eight levels were excellent fusion. Conclusion Patients receiving ACDF with local bone graft combined with a PEEK cage had significantly shorter operation time, lower perioperative complication rates, and better radiological results comparing with those with an iliac bone graft alone. It seems that the local bone graft with a PEEK cage appears to be a safe alternative to the iliac bone graft for ACDF.
颈前路椎间盘切除术和聚醚醚酮笼融合治疗退行性椎间盘病
背景颈椎前路椎间盘切除术已被证明是治疗退行性椎间盘疾病安全有效的方法。前路入路可以直接看到整个间隙,并广泛减压颈脊髓和神经根的前部;它可以在多节段疾病的情况下进行,如果需要,可以进行椎体间融合。患者与方法回顾性分析2012 - 2014年门诊部就诊的20例有症状的颈椎间盘病患者,年龄20 ~ 65岁,其中女性16例,男性4例,平均年龄43.25±9.06岁(范围28 ~ 60岁)。单纯神经根病13例(65%),单纯肌根病2例(10%),单纯神经根病5例(10%);根据Ranawat分级法对7例肌病进行分级。20名患者中有37个水平受到影响。C5、6是最常见的1级(40.5%),其次是C4、5、11(29.7%),其次是C6、7、7(18.9%),最少的是C3、4、4(10.8%)。显微镜下手术5例。采用聚醚醚酮(PEEK)笼和局部植骨进行前路颈椎椎间盘切除术和融合术(ACDF)。结果显微镜下平均手术时间为64.5 min,非显微镜下平均手术时间为47 min。术中唯一的并发症是颈外静脉结扎,发生在两例(非显微镜)。唯一的术后并发症是吞咽困难,13例发生吞咽困难(11例非镜下观察,2例镜下观察)。术前体间比值平均值为1.8±0.2,术后12个月平均值为1.9±0.2。术前和12个月时体间比值的平均值差异有统计学意义。术前平均椎间盘间隙高度3.3±0.8 mm,术后12个月平均椎间盘间隙高度5.8±0.9 mm。术前和术后12个月椎间盘间隙平均高度差异有统计学意义。12个月融合率:平均融合3个节段,良好融合26个节段,优秀融合8个节段。结论与单纯髂骨移植相比,ACDF联合局部植骨联合PEEK保持器手术时间明显缩短,围手术期并发症发生率明显降低,影像学效果更好。对于ACDF,局部骨移植物与PEEK笼似乎是一种安全的替代髂骨移植物。
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