Creation of a Database Including a Set of Biological Features Related to Protein Sequences and Their Corresponding Alignment

Francisco M. Ortuño Guzman, H. Pomares, I. Rojas, O. Valenzuela
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Abstract

There are currently several biological databases related to proteins depending on the information we are interested to extract. Therefore, since a heterogeneous set of features will be needed (domains, structures, ontology terms, etc), several quite different databases should be consulted. The handling of different databases can become difficult, as each database could provide a different nomenclature for the same proteins. Anyway, these databases usually provides some mapping tools in order to determine the correspondence among the different nomenclatures used for the same protein. The main goal of this paper is to provide a biological database including a huge amount of protein information in order to be used for different purposes in bioinformatics. This database will be designed as a flexible and extensible tool and it could be extended and updated when new proteins are annotated or the included ones are modified.
创建一个数据库,包括一组与蛋白质序列相关的生物特征及其相应的比对
目前有几个与蛋白质相关的生物数据库,这取决于我们感兴趣的信息提取。因此,由于需要一组异构的特征(领域、结构、本体术语等),因此应该参考几个完全不同的数据库。处理不同的数据库可能会变得很困难,因为每个数据库可能为相同的蛋白质提供不同的命名法。无论如何,这些数据库通常提供一些映射工具,以便确定用于同一蛋白质的不同命名之间的对应关系。本文的主要目标是提供一个包含大量蛋白质信息的生物数据库,以便在生物信息学中用于不同的目的。该数据库将被设计成一个灵活和可扩展的工具,当新的蛋白质被注释或被修改时,它可以被扩展和更新。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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