Effects of changes in drinking habits on lifestyle-related diseases

Health Evaluation and Promotion Pub Date : 2019-07-10 DOI:10.7143/jhep.46.431

Sei‐ichiro Kojima, N. Watanabe, S. Takashimizu, Kazuya Anzai, S. Tsuda, Hiroyuki Ito, J. Nagata, H. Ichikawa, K. Shiraishi, Y. Nishizaki

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引用次数: 1

Abstract

11,781 check-ups (7.3%), 8,548 check-ups (5.3%) and 6,335 check-ups (3.9%), respectively. Finally, the analysis was conducted with data from 117,730 health check-ups for 19,382 people. The subjects were 10,757 men (55.5%) and 8,625 women (44.5%). At the time of evaluation, their ages ranged from 21 to 98 years old, with a mean age of 57.8±10.9 years. The mean age of men was 58.2±11.0 years and that of women was 57.4±10.8 ABSTRACT Objectives Drinking habits are closely associated with various lifestyle-related diseases. We investigated the effects of changes in alcohol consumption on lifestyle-related disease in subjects who underwent multiple health check-ups at the Tokai University Hospital Health Check-up Center. Design Study of causation. Methods The subjects were 19,382 repeated examinees who underwent multiple health check-ups at the Health Check-up Center in our hospital from 2005 to 2015. Using the questionnaire method, the drinking quantity was estimated, and the effect of the change on the parameter (body mass index (BMI), systolic blood pressure (SBP), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), fasting blood glucose (FBG), uric acid (UA)) of the life-style related disease was analyzed, when the drinking quantity changed in first health check-ups and last health check-ups. Results BMI, SBP, TG, FBG, and UA all worsened in a dose-dependent manner with increases in alcohol consumption, and improved when alcohol consumption decreased. HDL-C improved with increased alcohol consumption in a dose-dependent manner, and worsened with a decrease in alcohol consumption. The increase in alcohol consumption contrib-uted to the development of metabolic syndrome, but it was through the deterioration of the parameters of lifestyle-related diseases and was not an independent factor. Conclusion Increased alcohol consumption during the course of observation positively affected HDL-C but negatively affected all other lifestyle-related disease parameters.

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饮酒习惯改变对生活方式相关疾病的影响

检查次数分别为11781次(7.3%)、8548次(5.3%)和6335次(3.9%)。最后，对19382人的117730次健康检查数据进行了分析。研究对象为10757名男性(55.5%)和8625名女性(44.5%)。评估时年龄21 ~ 98岁，平均年龄57.8±10.9岁。男性平均年龄58.2±11.0岁，女性平均年龄57.4±10.8岁。【摘要】目的饮酒习惯与各种生活方式相关疾病密切相关。我们调查了在东海大学医院健康检查中心接受多次健康检查的受试者中饮酒变化对生活方式相关疾病的影响。因果关系研究。方法选取2005 - 2015年在我院健康体检中心进行多次健康检查的重复体检者19382例为研究对象。采用问卷调查法估计饮酒量，分析首次健康检查和末次健康检查饮酒量变化对生活方式相关疾病的体质指数(BMI)、收缩压(SBP)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、甘油三酯(TG)、空腹血糖(FBG)、尿酸(UA)等参数的影响。结果BMI、收缩压、TG、FBG和UA均呈剂量依赖性随饮酒量增加而恶化，随饮酒量减少而改善。HDL-C随酒精摄入量的增加呈剂量依赖性改善，随酒精摄入量的减少而恶化。酒精消费的增加促进了代谢综合征的发展，但它是通过与生活方式有关的疾病参数的恶化而产生的，并不是一个独立的因素。结论观察期间饮酒增加对HDL-C有积极影响，但对所有其他与生活方式相关的疾病参数有负面影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Health Evaluation and Promotion

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