Seroprevalence of Chlamydia trachomatis types in children with clinical trachoma in New Delhi, India.

V N Kumar, M Sujata, G Satpathy
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Abstract

Micro-immunofluorescence test with type specific antigens of ocular Chlamydial infection types A-D was used for serotyping the causative C. trachomatis serotypes in 32 inclusion positive school children suffering from trachoma. Single serotype associated infection was seen in six of the patients. The rest of them had antibodies against more than one serotype indicating simultaneous or previous infection by more than one serotype. By geometric mean titre determination, type C appeared to be the most prevalent serotype. However the highest antibody titres in individual cases were most frequently observed for serotype A. The use of geometric mean titre versus highest titre against specific serotype observed in individual cases for population survey is discussed. Isolation of organism for absolute determination of causative serotype from each patient is emphasised.

印度新德里临床沙眼患儿沙眼衣原体类型血清患病率
应用眼衣原体感染A-D型特异性抗原微免疫荧光法对32例沙眼包涵阳性学龄儿童进行致病性沙眼衣原体血清型分型。6例患者出现单一血清型相关感染。其余的人有针对不止一种血清型的抗体,表明同时或以前感染过不止一种血清型。通过几何平均滴度测定,C型似乎是最普遍的血清型。然而,在个体病例中最高的抗体滴度最常被观察到为血清型a。使用几何平均滴度与最高滴度对特定血清型在个体病例中观察到的人口调查进行讨论。强调从每个病人身上分离有机体以绝对确定致病血清型。
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