[Formation of E-rosettes in homozygous nude mice (nu/nu) and heterozygotes (nu/+)].

Archivos de investigacion medica Pub Date : 1990-10-01
R Ramos-Zepeda, Y Ramos-Zepeda, A González-Mendoza, R Ramos-Zepeda
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Abstract

Nude homozygote nu/nu mice show a deficiency in their cellular immune response, due to the fact that their thymic tissue is very scarce. The purpose of this paper has been to determine whether nu/nu mice, in the presence of T lymphocytes, have the capacity of forming E rosettes with sheep erythrocytes. These mice do present them, although in significantly lower quantities when compared to the nu/+ and normal ones of Balb/c strain. This result confirms previous information which point towards the existence of other types of markers on the surface of T lymphocytes in nu/nu mice.

[纯合子裸鼠(nu/nu)和杂合子(nu/+) e -莲座的形成]。
裸纯合子nu/nu小鼠表现出细胞免疫反应的缺陷,因为它们的胸腺组织非常稀少。本文的目的是确定在T淋巴细胞存在的情况下,nu/nu小鼠是否具有与羊红细胞形成E莲座的能力。这些小鼠确实出现了它们,尽管与Balb/c株的nu/+和正常小鼠相比,它们的数量明显较低。这一结果证实了nu/nu小鼠T淋巴细胞表面存在其他类型标记的先前信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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