[The realities and paradoxes in the nephrotic syndrome with minimal glomerular lesions in children].

Abstract

On the basis of the present knowledge in the nephrotic syndrome with minimum glomerular lesions, the paper reviews the paradoxes of the disease: the glomeruli with normal histologic structure in optic microscopy, but with the highest proteinuria in the whole human pathology; absence of some clear arguments concerning the existence of the immunologic disorders, but the best medication is corticotherapy and immunodepressive drugs; the high incidence of the allergic background against which the nephrotic syndrome appears, but with or without a limited effect of the antiallergic medication. The above-mentioned elements may be interesting research fields in the future.