Fabrication of 3D capillary vessel simulator using femtosecond laser and mask hybrid exposure

Abstract

Circulation-type blood vessel model can contribute to evaluation of drag delivery systems and the alternative systems for animal test. The shape of conventional models fabricated by photolithography is limited to two dimensions (2D). Therefore, we needed to fabricate three-dimensional (3D) blood vessel models for simulating real blood vessel shapes. For this purpose, we propose a novel 3D exposure method as femtosecond laser and mask hybrid exposure: FMEx. FMEx is integrated two-photon absorption exposure method by using femtosecond laser and photolithography method by using mask aligner. We report the results of fabricated 3D capillary vessel model by using FMEx.