Magnetic Nanoparticles: from Synthesis to Theranostics

Abstract

Magnetic nanoparticles (MNPs), particularly made of iron oxides, hold great promise for biomedical theranostic applications particularly as diagnostic imaging agents and drug delivery carriers. Such potential stems from their unique intrinsic physiochemical and biochemical properties including excellent magneto-responsive properties, low toxicity, colloidal stability, and facile surface engineering capability. Herein, the most prominent synthetic approaches employed for preparation of biocompatible colloidal MNPs utilized for biomedical endpoints are outlined. Particular attention is devoted to the utilization of MNPs as multimodal imaging agents with notable examples presented. Undoubtedly, in the upcoming years, MNP formulations will serve as potentially promising diagnostic and therapeutic candidates in magneto-responsive medical theranostics.