Wolfram Syndrome; Case Series Report at the “National Medical Center 20 De Noviembre ISSSTE”

Abstract

Wolfram syndrome it’s a rare autosomal genetic disease. Also, kwon as DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness). Its classified as one of infancy onset diabetes mellitus non autoimmune causes, its presentation generally happens at an early age; other characteristics of the disease are insipidus diabetes, optic atrophy, neurosensorial deafness, psychiatric alterations and other neurodegenerative disorders.