A tree structure-based classification of diabetic retinopathy stages using convolutional neural network

M. S. H. Peiris, S. Sotheeswaran
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Abstract

Detection, and classification of medical images have become a trending field of study during the last few decades. There is a considerable amount of vital challenges to be overcome. Ample work has been carried out to provide proper solutions for those key challenges. This study was carried out to extend one such medical image classification process to classify the stages of Diabetic Retinopathy (DR) images from colour fundus images. The study proposes a novel Convolutional Neural Network (CNN) architecture which is considered to be one of the most trending and efficient forms of classification of DR stages. Initially, the preprocessing techniques were employed to the DR fundus images with Green channel extraction and Contrast Limited Adaptive Histogram Equalization (CLAHE). The data augmentation strategy was utilised to increase training images from the DR images. Finally, Feature extraction and classification were carried out by using the proposed CNN architecture. It consists of a 14 layered CNN model, which continues three main classifications. In this proposed classification, the images were classified into a tree structure based binary classification as No_DR and DR at the beginning, and then the DR images were again classified into two classes, namely Pre_Intermediate and Post_Intermediate. Moreover, those two classes were again separately classified into Mild, Moderate, and Proliferate_DR, Severe, respectively. The Kaggle is one of the benchmark dataset repositories which was used in this study. The proposed model was able to achieve accuracies of 81 %, 96%, 84%, and 97% for the above-mentioned classifications, respectively.
基于卷积神经网络的糖尿病视网膜病变分期树状结构分类
在过去的几十年里,医学图像的检测和分类已经成为一个趋势研究领域。有相当多的重大挑战需要克服。已经进行了大量工作,为这些关键挑战提供适当的解决办法。本研究旨在扩展一种医学图像分类过程,从彩色眼底图像中对糖尿病视网膜病变(DR)图像进行分期分类。该研究提出了一种新颖的卷积神经网络(CNN)架构,被认为是最流行和最有效的DR阶段分类形式之一。首先,采用绿色通道提取和对比度有限自适应直方图均衡化(CLAHE)技术对DR眼底图像进行预处理。利用数据增强策略从DR图像中增加训练图像。最后,利用本文提出的CNN架构进行特征提取和分类。它由一个14层的CNN模型组成,该模型延续了三个主要分类。在本文提出的分类中,首先将图像分为基于树结构的二值分类No_DR和DR,然后将DR图像再次分为Pre_Intermediate和Post_Intermediate两类。此外,这两个类别再次分别被分为轻度,中度和增殖,严重。Kaggle是本研究中使用的基准数据库之一。对于上述分类,所提出的模型分别能够达到81%、96%、84%和97%的准确率。
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