The Use of Thoracic Epidural for Rapid Opioid Taper

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Abstract

BACKGROUND: Inflammatory Bowel Disease (IBD) is often associated with significant abdominal pain that can be challenging to control. Although controversial, opioids are often prescribed for the management of abdominal pain in patients with IBD. There have been several methods described for the rapid taper of patients on long-term, high-dose opioids. However, to date, there have been no reported cases using epidural analgesia for rapid opioid taper. CASE REPORT: We present a case of a 36-year-old man with ulcerative colitis and recurrent bowel obstructions on a high-dose transdermal fentanyl patch whose opioid consumption was rapidly tapered during inpatient hospitalization utilizing thoracic epidural analgesia. CONCLUSION: The potential role of epidural analgesia in rapid opioid taper has yet to be explored. In patients with chronic pain and inflammatory bowel disease or recurrent bowel obstructions, epidural analgesia may be particularly helpful to improve gastrointestinal motility while also being used to rapidly taper opioid dosage. KEY WORDS: Inflammatory bowel disease, ulcerative colitis, Crohn’s disease, epidural, opioids, rapid opioid taper, fentanyl patch
胸椎硬膜外麻醉用于阿片类药物快速减径
背景:炎症性肠病(IBD)常伴有难以控制的明显腹痛。尽管存在争议,但阿片类药物经常被用于治疗IBD患者的腹痛。已有几种方法描述了患者长期高剂量阿片类药物的快速减少。然而,到目前为止,还没有使用硬膜外镇痛来快速减少阿片类药物的病例报道。病例报告:我们提出了一个病例,36岁的男子溃疡性结肠炎和复发性肠梗阻的高剂量透皮芬太尼贴片,其阿片类药物消耗迅速减少住院期间使用胸椎硬膜外镇痛。结论:硬膜外镇痛在阿片类药物快速减少中的潜在作用有待探讨。对于慢性疼痛和炎症性肠病或复发性肠梗阻患者,硬膜外镇痛可能特别有助于改善胃肠道运动,同时也可用于迅速减少阿片类药物的剂量。关键词:炎症性肠病,溃疡性结肠炎,克罗恩病,硬膜外,阿片类药物,阿片类药物快速减少,芬太尼贴剂
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