Self-Assembling Property of Graphene Derivates Chemico-Physical and Toxicological Implication

Abstract

This work start after seeing an recent open letter for transparency related production an quality control technique of mRNA vaccine first signed by Tarro G, Luisetto M and Monsellato ML and an editorial recognized by IMA Marijnskaya academy: Graphene and Derivate: Physio-Chemical and Toxicology properties in the mRNA Vaccine Manufacturing Strategy, needed specific proof of absence for the regulatory aspects (accepted for publication). Other relevant evidences related to this topic comes from the work of Giovannini, et al. related Dark field microscope assay of the blood of 1086 symptomatic subjects after vaccination with two types of m-RNA vaccine of great interest on this field also the work of P Campra and Young RO, Young Me Lee or Ki-Yeob J. Observing all this recent evidences the aim of this work is to investigate not only the graphene presence (or not) in vials of mRNA Vaccine but also the self-auto assembly properties of graphene and derivate. This is in order to find relationship in some biotechnological application like m-RNA Vaccine’s large scale production. After a review part an experimental hypothesis project will be submitted to the researcher to produce a global conclusion related the topic investigated. The recent evidences published induced the idea to more deeply study these properties for the clinicotoxicological aspects involved. The pro-coagulant properties of the coronavirus covid-19 Spike Protein are well knower by scientific literature as well as the toxicological profile of the graphene derivate. What can happen if this two substantive can act in patients with platelet disorder in the same time?