A new approach to testing the toxicity of substances and materials during fires

S. Puzach, Nikita V. Komarevtsev, Nataliya V. Koroleva, T. Merkushkina
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Abstract

PURPOSE. The aim of the research was to investigate methods for assessing the hazard of combustion products of substances and materials during fires in terms of their toxicity and to formulate a new approach to testing. METHODS. The authors conducted an analytical review of experimental methods for studying the toxicity of substances and materials during fires. The database of a standard fire load was analyzed in terms of carbon monoxide evacuation route blocking. FINDINGS. The analysis of experimental methods for studying the toxicity of substances and materials, as well as the database of a standard fire load, showed that standard tests do not allow for a correct assessment of combustion products toxicity in view of ensuring safe evacuation of people at fires. A new criterion for determining the level of toxicity of combustion products has been proposed, and a new approach to toxicity testing has been justified. RESEARCH APPLICATION FIELD. The results can be used to rank the toxicity of combustion products of substances and materials during fires based on the criterion of ensuring safe evacuation of people. CONCLUSIONS. It has been determined that standard tests cannot correctly assess the toxicity of substances or materials as regards safe evacuation of people. None of the existing installations can determine the toxicological hazard criterion KТО. Therefore, for experimental research on the toxicity of combustion products of substances and materials based on the proposed criterion, tests can be conducted on complementary setups.
一种测试火灾中物质和材料毒性的新方法
目的。这项研究的目的是研究评估火灾中物质和材料燃烧产物的毒性危害的方法,并制定一种新的测试方法。方法。对火灾中物质和材料毒性研究的实验方法进行了分析综述。从一氧化碳疏散路径阻塞的角度分析了标准火灾负荷数据库。发现。对研究物质和材料毒性的实验方法以及标准火灾负荷数据库的分析表明,为了确保在火灾中安全疏散人员,标准测试无法正确评估燃烧产物的毒性。提出了一种确定燃烧产物毒性水平的新标准,为毒性检测提供了一种新的方法。研究应用领域。研究结果可以在保证人员安全疏散的基础上,对火灾中物质和材料燃烧产物的毒性进行排序。结论。已经确定,在安全疏散人员方面,标准测试不能正确评估物质或材料的毒性。现有的设施都不能确定毒理学危害标准KТО。因此,对于基于该准则的物质和材料燃烧产物毒性的实验研究,可以在互补装置上进行试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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