Accurate attenuation correction in SPECT without transmission measurements

Abstract

The current trend in attenuation correction for SPECT is to measure and reconstruct the attenuation coefficient map using a transmission scan, performed either sequentially or simultaneously with the emission scan. This approach requires dedicated hardware and increases the cost (and in some cases the scanning time) required to produce a clinical SPECT image. Furthermore, if short focal length fan-beam collimators are used for transmission imaging, the projection data may be truncated, leading to errors in the attenuation coefficient map. Our goal is to obtain information about the attenuation distribution from only the measured emission data by exploiting the fact that only certain attenuation distributions are consistent with a given emission dataset. Ultimately this consistency information will either be used directly to compensate for attenuation or combined with the incomplete information from fan-beam transmission measurements to produce a more accurate attenuation coefficient map. The simulations and phantom studies performed in this investigation show that, in certain circumstances, the consistency conditions of the SPECT data can be used to produce an accurate estimate of the attenuation map without performing any transmission measurements.