Improvement of Mechanical Properties of 3d Printed Hydroxyapatite Scaffolds by Polymeric Infiltration

S. Stevanovic, P. Chavanne, O. Braissant, U. Pieles, P. Gruner, R. Schumacher
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引用次数: 16

Abstract

Tailor made bioceramic scaffolds in combination with the corresponding surface chemistry and biology is of great importance for a successful implantation and rapid osseo-integration. The present study investigates the fabrication of Hydroxyapatite (HA) scaffolds with defined macro porosity by means of powder based 3D-printing. In order to mime natural bone with its elastic collagen structure, the 3D-printed ceramic structures were post-treated by polymeric infiltration. Compressive Strength analysis (CS) confirmed the positive impact of an elastomeric phase on mechanical properties. 3D-printed HA scaffolds in combination with polymer result in biodegradable scaffolds with promising mechanical properties for potential use in regenerative medicine.
聚合物浸润改善3d打印羟基磷灰石支架的力学性能
结合相应的表面化学和生物学,定制生物陶瓷支架对于成功植入和快速骨整合具有重要意义。本研究利用粉末基3d打印技术制备具有宏观孔隙度的羟基磷灰石(HA)支架。为了模拟具有弹性胶原结构的天然骨,3d打印陶瓷结构采用聚合物浸润后处理。抗压强度分析(CS)证实了弹性体相对机械性能的积极影响。3d打印的透明质酸支架与聚合物相结合,产生了具有良好机械性能的可生物降解支架,在再生医学中具有潜在的应用前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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