Electrical Brain Stimulation for Punishment and Reward

Youjin Lee, S. Jun
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Abstract

Recently, electrical stimulation on the brain has been widely used for neuroscience research as well as medical purposes such as deep brain stimulation (DBS), cochlear implant, and spinal cord stimulation [1]–[3]. In this study, electrical brain stimulation was employed to control rodent's movement behaviors. Tungsten wire electrodes were characterized and implanted into the target regions of rat brain. Two brain areas were targeted; medial forelimb bundle (MFB) and amygdala as a reward and punishment, respectively. MFB is known to be related with learning and memory while amygdala is the center for fear modulation in the brain. The stimulation-induced behaviors of rats were monitored and analyzed for both reward and punishment.
脑电刺激的惩罚和奖励
近年来,脑电刺激已广泛应用于神经科学研究和医学用途,如深部脑刺激(DBS)、人工耳蜗、脊髓刺激等[1]-[3]。本研究采用脑电刺激控制啮齿动物的运动行为。对钨丝电极进行了表征,并将其植入大鼠脑靶区。两个大脑区域被瞄准;内侧前肢束(MFB)和杏仁核分别作为奖励和惩罚。MFB与学习和记忆有关,杏仁核是大脑中调节恐惧的中心。对大鼠的刺激诱导行为进行了奖惩监测和分析。
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