Advances in Modeling Dielectric Response of Biological Structures at Microscopic Level

P. Marracino, A. De Angelis, E. Limiti, M. Cristofanon, A. Denzi, F. Andre, L. Mir, F. Apollonio, M. Liberti
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Abstract

The use of dielectric response as a tool for studying molecular and cellular parameters is a well-established approach on continuing attention. A valuable approach, which is used to gather inside mechanisms of dielectric response and to provide the average electrical parameters of both the cell membrane and the intra-cellular and extracellular medium, is represented by the modeling one. In this paper we will describe some advances in models able to describe the dielectric behavior of different bio-systems, in particular: molecular models for Na+ and Cl-ion in water and water in proximity of charged surfaces and cell continuum microdosimetric models.
生物结构介电响应微观模拟研究进展
使用介电响应作为研究分子和细胞参数的工具是一种持续关注的行之有效的方法。建模方法是一种有价值的方法,用于收集介电响应的内部机制,并提供细胞膜以及细胞内和细胞外介质的平均电参数。在本文中,我们将描述一些能够描述不同生物系统介电行为的模型的进展,特别是:Na+和cl -离子在水中和靠近带电表面的水的分子模型和细胞连续微剂量学模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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