Pre-clinical evaluation of the treatment with MSCs of fistular pathology in inflammatory bowel diseases

Abstract

Perianal disease includes the presence of fistulas, abscesses, fissures and stenoses that place a burden on the patient due to perianal losses, pain and a decrease in quality of life. It is a disease in which the body produces an immune reaction against itself. The traditional treatment of this pathology includes the use of antibiotics and immunomodulatory drugs or surgery. However, surgery may not always be performed due to the inherent risk of the procedure or the incontinence sequelae it may cause.