Flow Properties of Heterogeneous Turbid Media Probed by Diffusing Temporal Correlation

D. Boas, I. Meglinsky, L. Zemany, L. Campbell, B. Chance, A. Yodh
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引用次数: 1

Abstract

Variations in the amplitude and phase of diffuse photon density waves is known to yield important information about the structural properties of turbid media, such as the scattering and absorption coefficients. Information on the dynamical properties of turbid media may be obtained from the temporal fluctuations of light fields emanating from the media. In this contribution, we demonstrate that variations in temporal correlation functions of the temporal intensity fluctuations of different speckles of light can be used to derive information about the spatially varying dynamical properties of turbid media. We first present a diffusion for the temporal correlation function for systems where the dynamics are governed by Brownian motion and shear and random flow. We demonstrate the validity of the correlation diffusion for heterogeneous systems by comparing the theoretical results with experimental results for systems governed by different dynamical processes, e.g. flow. As an illustration of the usefulness of this correlation technique to biomedical optics, we discuss the application of this technique to diagnosing the thickness of burned tissue. The correlation diffusion is an important, unique tool for analyzing the complex dynamical signals that arise from heterogeneous biological systems.
用扩散时间相关性研究非均匀浑浊介质的流动特性
众所周知,扩散光子密度波的振幅和相位的变化可以提供有关浑浊介质结构特性的重要信息,例如散射和吸收系数。关于浑浊介质动力学特性的信息可以从介质发出的光场的时间波动中获得。在这篇贡献中,我们证明了不同光斑的时间强度波动的时间相关函数的变化可以用来推导有关浑浊介质的空间变化动态特性的信息。我们首先提出了系统的时间相关函数的扩散,其中动力学由布朗运动、剪切和随机流动控制。我们通过对不同动力过程(如流动)控制的系统的理论结果与实验结果的比较,证明了相关扩散对异质系统的有效性。为了说明这种相关技术对生物医学光学的有用性,我们讨论了该技术在诊断烧伤组织厚度方面的应用。相关扩散是分析异质生物系统产生的复杂动态信号的一种重要而独特的工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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