ROP REACTIVATED!

Abstract

Purpose:To report a case of ROP reactivation, later in life following natural regression in infancy.Methods:Prospective study focusing on ocular presentation and outcome of long term ROP follow-up at Tertiary Hospital, India. A 12-year-old female, seen by us first at 8 years of age, with a 6-monthly follow-up with known history of bilateral ROP came with complaints of black spots. The incident occurred after 4 years of follow-up in this patient at our center.On examination, patient had (OD) falciform fold at the macula and (OS) had regressed ROP. Left eye had developed new vascular buds (vessels) along avascular arcade. FFA was done and leaks with non-perfusion areas were noted. Patient didn’t receive any treatment in the past and was on 6 monthly follow-ups.Result:Based on the clinical symptoms and signs, reactivation of ROP was suspected and FFA examination revealed filing defects and leaks. After consent, laser therapy was given to stop the progression .Visual acuity and retina remained steady during the follow-up period. Bone densitometry done on patient showed low calcium levels.Conclusion: Patients with history of ROP treatment with or without active signs should be evaluated lifelong to detect and avert vision threatening complications.Keywords: ROP, Retinopathy of prematurity, retrolental fibroplasia