Qingzhu Zhang, H. Tu, H. Yin, F. Wei, Hongbin Zhao, Chunling Xue, Qianhui Wei, Zhaohao Zhang, Xiao Zhang, Shaoming Zhang, Q. Han, Yudong Li, R. Zhao, Jiang Yan, Junfeng Li, Wenwu Wang
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引用次数: 12
Abstract
In this paper, a biocompatible biosensor based on horizontal Si nanowire (NW) array field-effect transistor (FET) has been fabricated by the feasible spacer image transfer (SIT) process. The Si NW FET as biosensor is proposed for the realtime cellular Ca2+ monitoring for mesenchymal stem cells (MSCs), which presents fast-responded and high-sensitive characteristics. Compared with the conventional sensing techniques, the Si NW biosensor exhibits non-invasive, biocompatible and reliable advantages. This will help us to further understand the mechanism of cellular ion activities and provides a promising method for the cell-level diagnose and therapy.
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