Paraphenylene diamine (Kala Pathar) poisoning in children of Bahawalpur and surrounding areas

Sumera Akram, Muhammad Ahmed Khan, Imran Qaisar, Abdul Rehman, Wasif Ijaz, S. Khalid
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Abstract

Background: Paraphenylene diamine (commonly known as Kala Pathar in Pakistan) poisoning is a common presentation in adults as well as pediatric patients in Southern Punjab. The study was carried out to assess paraphenylene diamine poisoning in pediatric cases. Patients and methods: The cross-sectional study was carried out at Bahawal Victoria Hospital Bahawalpur. All the pediatric cases (<15 years age) of paraphenylene diamine poisoning reported during April 2021 to April 2022. Data was entered and analyzed in SPSS. Results: Total 84 children presented at pediatric department of the hospital. Out of these, 43 (51.2%) were males and 41 (48.8%) were females. Age range was between 02 months and 15 years, mean age being 9.4 + 4.49 years. Majority of cases (46.6%) ingested paraphenylene diamine accidentally, followed by suicidal intention (29.8%), homicidal intent (21.4%) and unknown motive in 2.4% cases. Of all, 49 (58.3%) died of poisoning and 35 (41.7%) survived. Of all the cases, 44 (52.4%) underwent emergency tracheostomy. Conclusions: Paraphenylene diamine poisoning in children is an alarming trend. Although majority of the cases ingested it accidently but intake due to suicidal or homicidal reason were also high. Positive outcome was associated with higher age, carrying out early tracheostomy and mode of poisoning (homicidal cases had poorest outcome whereas accidental and suicidal pediatric cases had more chances of survival).
巴哈瓦尔布尔及周边地区儿童对苯二胺(Kala Pathar)中毒
背景:对苯二胺(在巴基斯坦通常称为Kala Pathar)中毒是旁遮普南部成人和儿科患者的常见症状。本研究旨在评估小儿对苯二胺中毒病例。患者和方法:横断面研究在巴哈瓦尔布尔的巴哈瓦尔维多利亚医院进行。2021年4月至2022年4月期间报告的所有儿童(15岁以下)对苯二胺中毒病例。在SPSS中输入数据并进行分析。结果:84例患儿在该院儿科就诊。其中男性43例(51.2%),女性41例(48.8%)。年龄02个月~ 15岁,平均9.4 + 4.49岁。误食对苯二胺最多(46.6%),其次为自杀意图(29.8%)、杀人意图(21.4%)和不明动机(2.4%)。中毒死亡49例(58.3%),存活35例(41.7%)。其中44例(52.4%)行急诊气管切开术。结论:儿童对苯二胺中毒呈令人担忧的趋势。虽然大多数病例是意外摄入的,但自杀或杀人原因摄入的也很高。阳性结果与较高的年龄、早期进行气管切开术和中毒方式相关(杀人病例预后最差,而意外和自杀的儿科病例有更多的生存机会)。
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