The Role of Infections in Human Pathology

V. Maleev, V. Akimkin, A. Ploskireva, S. Ugleva
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Abstract

Infectious diseases, due to their epidemic potential, are capable of global spread, they are unpredictable, and their effective control is possible only on a planetary scale. In no other field of medicine, such radical and often unpredictable changes occur in a short time in the form of the elimination of individual diseases, the identification of a large number of previously unknown and the return of already forgotten diseases, a significant change in the pathogenesis and clinical symptoms of a significant number of them. Under these conditions, these changes often create problems for the health authorities and the public, ahead of their ability to recognize and respond in a timely manner to the emergence of epidemics and the transformation of pathological manifestations. Significant recent scientific progress has only slightly clarified our knowledge of the biological and genetic diversity of pathogens. Until now, the entire spectrum of infectious pathology remains unclear, and its numerous manifestations often take even experienced specialists by surprise. Evidence of our limited knowledge and ability to control the situation is the ongoing COVID-19 pandemic for three years now, the increasingly frequent detection of new infections, the return of infections declared defeated, evidence of the role of infectious factors in the etiology of many other human diseases.
感染在人类病理学中的作用
传染病由于具有流行病的潜力,有可能在全球蔓延,它们是不可预测的,只有在全球范围内才能对其进行有效控制。在任何其他医学领域,都不会在短时间内发生这种彻底的、往往不可预测的变化,其形式是消除个别疾病,发现大量以前未知的疾病,并使已经被遗忘的疾病卷土重来,其中相当一部分疾病的发病机制和临床症状发生重大变化。在这种情况下,这些变化往往给卫生当局和公众带来问题,使他们无法及时认识和应对流行病的出现和病理表现的转变。最近重大的科学进展只是稍微澄清了我们对病原体的生物和遗传多样性的认识。直到现在,整个感染病理谱仍不清楚,其众多的表现往往使经验丰富的专家感到惊讶。我们控制疫情的知识和能力有限的证据是,COVID-19大流行已经持续了三年,新感染的发现越来越频繁,宣布失败的感染再次出现,感染因素在许多其他人类疾病的病因学中发挥作用的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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