The COVID-19 infection from the perspective of the gastroenterologist

M. Branković, I. Jovanovic, T. Radonjić, O. Markovic, Milica Brajkovic, V. Popadić, S. Klašnja, M. Zdravković
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Abstract

The gastrointestinal tract and liver are not spared, when it comes to the coronavirus disease of 2019 (COVID-19), as it doesn't only affect the respiratory tract, but it is also a systemic disease that causes multiple organ damage. In this review, we have united all information that is clinically significant for physicians dealing with this infection, especially for gastroenterologists. One must bear in mind that gastrointestinal symptoms can be the first and/or only indicators of COVID-19, so this infection needs to be suspected when a patient at risk presents with diarrhea, loss of appetite, abdominal pain, nausea, and/or vomiting. Upper gastrointestinal endoscopy in the COVID-19 pandemic is a major issue, as transmission of this airborne infection happens very easily during this procedure, and it should be performed only in cases of gastrointestinal emergencies. With regard to patients suffering from inflammatory bowel disease (IBD), they are often on immunosuppressive therapy, but recommendations are that no change in therapy should be made, as these patients do not fall under the category of patients who are at increased risk of contracting COVID-19. In addition, liver lesion caused by this infection develops as the result of a multifactorial mechanism and is a definite cause for concern, especially in patients with pre-existing chronic liver conditions, who should be closely monitored.
从胃肠病学角度看COVID-19感染
当谈到2019年的冠状病毒病(COVID-19)时,胃肠道和肝脏也不能幸免,因为它不仅影响呼吸道,而且是一种导致多器官损伤的全身性疾病。在这篇综述中,我们汇集了所有对处理这种感染的医生,特别是胃肠病学家具有临床意义的信息。必须记住,胃肠道症状可能是COVID-19的首要和/或唯一指标,因此,当有风险的患者出现腹泻、食欲不振、腹痛、恶心和/或呕吐时,需要怀疑这种感染。在COVID-19大流行期间,上消化道内窥镜检查是一个主要问题,因为这种空气传播感染在这一过程中非常容易传播,只有在胃肠道紧急情况下才应该进行。对于患有炎症性肠病(IBD)的患者,他们通常接受免疫抑制治疗,但建议不改变治疗方法,因为这些患者不属于感染COVID-19风险增加的患者类别。此外,这种感染引起的肝脏损害是一个多因素机制的结果,是一个明确的引起关注的原因,特别是在已有慢性肝病的患者中,应该密切监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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