A study on effect of glycemic control on cardiac autonomic function tests in type 2 diabetes

Abstract

The present study was undertaken to estimate the glycosylated Hb level in type-2 diabetic subjects by cation-exchange- resin method and to study the relation between glycemic control and cardiac autonomic function. The study comprised of 90 subjects, 60 Diabetic mellitus type 2 patients and 30 age matched normal individuals. Diabetic mellitus type 2 patients were further classified in to two sub-groups, Type2 Diabetic mellitus patients with good glycemic control (HbA1c 7). The basis of finding is multifactorial and may be at multiple levels of neuraxis including peripheral and central mechanisms as reviewed under pathophysiology of diabetic autonomic neuropathy.