Spontaneous intracranial haematoma

B. Orakcioglu, A. Unterberg
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Abstract

Spontaneous intracranial haematomas remain a challenging pathology with high morbidity and mortality (60–80% of long-term disability). Despite decades of the search for specific treatments no evidence has yet been found for neither conservative nor surgical treatment in randomized controlled studies. While patients with space occupying infratentorial haematomas are more likely to benefit from surgery treatment of supratentorial haemorrhages remains controversial. Recent studies suggest that minimally invasive surgery including endoscopy to evacuate intracranial haematoma may be more effective than conservative treatment or standard surgical craniotomy (MISTIE II). Future studies (i.e. MISTIE III, MISTICH, SWITCH) will hopefully demonstrate evidence for individualized treatments.
自发性颅内血肿
自发性颅内血肿仍然是一种具有高发病率和死亡率的具有挑战性的病理(60-80%的长期残疾)。尽管几十年来一直在寻找特定的治疗方法,但在随机对照研究中,还没有发现保守治疗和手术治疗的证据。虽然占位性幕下血肿患者更有可能受益于幕上出血的手术治疗,但仍有争议。最近的研究表明,微创手术包括内窥镜排出颅内血肿可能比保守治疗或标准手术开颅(MISTIE II)更有效。未来的研究(即MISTIE III, MISTIE, SWITCH)有望为个性化治疗提供证据。
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