N. V. Bobkova, R. Poltavtseva, Daria Zhdanova, V. Kovalev, A. Chaplygina
{"title":"THE EFFECT OF YB-1 PROTEIN IN СHIMERIC MODEL OF ALZHEIMER’S DISEASE","authors":"N. V. Bobkova, R. Poltavtseva, Daria Zhdanova, V. Kovalev, A. Chaplygina","doi":"10.47501/978-5-6044060-1-4.10","DOIUrl":null,"url":null,"abstract":"The paper focuses on the molecular cell interaction of human mesenchymal stromal cells with the hippocampal primary culture of transgenic XFAD mice and the effect of multifunctional YB-1 protein on the memory and state of adult neurogenesis niches in animals with a chi-meric model of Alzheimer's disease. The results suggest the usefulness of a comprehensive use of cell therapy in combination with YB-1 to activate compensatory mechanisms in patients with Alzheimer's disease.","PeriodicalId":302576,"journal":{"name":"Institute of information technology","volume":"2017 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Institute of information technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47501/978-5-6044060-1-4.10","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The paper focuses on the molecular cell interaction of human mesenchymal stromal cells with the hippocampal primary culture of transgenic XFAD mice and the effect of multifunctional YB-1 protein on the memory and state of adult neurogenesis niches in animals with a chi-meric model of Alzheimer's disease. The results suggest the usefulness of a comprehensive use of cell therapy in combination with YB-1 to activate compensatory mechanisms in patients with Alzheimer's disease.