Modern view on the problem of postoperative pulmonary embolism. Literature review

S. Fedorov, K. B. Vapaev, A. Medvedev, M. N. Kudykin, L. M. Tselousova
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Abstract

Pulmonary embolism (PE) occupies one of the leading positions in the structure of postoperative complications, while determining an extremely high mortality rate. Despite the advances in medicine in the prevention, diagnosis and treatment of this disease, the PE epidemiological thresholds have not changed significantly over the past twenty years. Today, despite the routine use of mechanical and pharmacological thromboprophylaxis, the 30-day mortality rate after major surgeries ranges from 16.9 % to 31 %. Considering that more than 300 million surgical interventions are performed in the world, and more than 10 million operations per year in the Russian Federation, the scale of the problem can be easily imagined. The results of numerous studies confirm that at present, the problem of postoperative PE remains extremely urgent and requires further study. This manuscript provides a review of modern literature highlighting the key issues of the studied pathology.
术后肺栓塞问题的现代认识。文献综述
肺栓塞(Pulmonary embol栓塞,PE)在术后并发症的结构中占据主导地位,同时具有极高的死亡率。尽管在预防、诊断和治疗该病的医学方面取得了进步,但在过去的20年里,PE的流行病学阈值并没有明显变化。今天,尽管常规使用机械和药物预防血栓,但大手术后30天死亡率从16.9%到31%不等。考虑到全世界进行了3亿多例外科手术,俄罗斯联邦每年进行1000多万例手术,不难想象问题的规模。大量研究结果证实,目前,术后PE问题仍然非常紧迫,需要进一步研究。这份手稿提供了现代文献的回顾,突出了研究病理的关键问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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