New Developments toward a Clinical Test of Retinal Ganglion Cell Function

Abstract

We recently developed a method for extracting a component from the human multifocal electroretinogram (ERG) that is generated by ganglion cells1,2. As its latency depends linearly on the estimated length of ganglion cell axons connecting the site of focal stimulation with the disc, this optic nerve head component (ONHC) is presumed to originate from the axons where myelination begins1,2. A second, retinal component (RC) has an invariant latency.