Effect of 12 Weeks of Intensive Interval and Combined Training on Apolipoprotein A and B, Visfatin and Insulin Resistance in Overweight Middle-Aged Women with Type 2 Diabetes

Abstract

Aims: Probabely through improvements in the levels of apolipoproteins (ApoA and ApoB) and visfatin, the sport activities helps to reduce the risks of cardiovascular diseases in the diabetic persons. The aim of this study was to compare the effects of intensive interval and combined trainings on the levels of ApoA and ApoB, visfatin, and insulin resistance in the middle-aged women with Type II diabetes. Materials & Methods: In the semi-experimental study, 52 middle-aged female patients with Type II diabetes were studied in Shahr-e-Kord in 2015. The subjects, selected by convenience sampling method, were randomly divided into three groups, incluing simultaneous strength-endurance training, interval intensive training, and control groups. 12-week trainings, composed of three endurance training sessions per week with 60% of maximum heart rate and two resistance training sessions per week with 70% of one maximum repetition, were done in strength-endurance group. Three training sessions per week with 4-10 repetition of 30-second Wingate test on the ergometer were conducted in interval intensive training group with maximum effort. Data was analyzed by SPSS 21 software using dependent T test, covariance analysis, and LSD test. Findings: At the post-test stage and following interval intensive trainings, ApoA reduction (p=0.03) and ApoB/ApoA (p=0.01) were significant. However, no significant difference was observed in combined group. The levels of visfatin and serum insulin and insulin resistance index significantly decreased in both training groups (p<0.01). Conclusion: The interval intensive trainings further affect the levels of blood apolipoprotein, visfatin, and insulin resistance in the middle-aged women with Type II diabetes, than the combined endurance-resistance trainings.