Hybrid APC Colon EMR, A Novel Approach to Reduce Local Recurrence

IF 1.2 Q4 GASTROENTEROLOGY & HEPATOLOGY
John M. Levenick , Andrew J. Groff , Carl Manzo , Courtney Lester , Jennifer L. Maranki
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引用次数: 2

Abstract

Background and Aims

Endoscopic mucosal resection (EMR) has become the standard for removing large colon polyps but has a 10%-30% recurrence rate using standard techniques. Data shows improved recurrence rates with focal therapy of the edge of the resection base using cautery. We examine a novel technique, hybrid APC assisted EMR, which treats both the edge and the base with cautery to assess its effect on local recurrence.

Methods

We reviewed all EMRs of polyps >2 cm by a single endoscopist with 6-month follow-up from May 2018 to November 2019 using both standard EMR as well as hybrid APC assisted EMR to assess local recurrence as well adverse events.

Results

Forty-eight patients with 59 polyps removed by EMR had full 6 month follow up with a mean age of 66.1 years of age, 45% were female. Thirty polyps were removed by hybrid APC assisted EMR and 29 removed with standard EMR. Overall, 0 (0%) polyps in the h-APC arm had local recurrence while 6 (20.7%) in the standard group had histological proven local recurrence (P = 0.01). Postresection bleeding occurred in 6 patients, 2 in the hAPC arm and 4 in the standard arm (P = 0.41).

Conclusion

In this retrospective pilot study, hybrid APC assisted EMR was superior to conventional EMR for local recurrence after removal of large colon polyps and trended towards a less post-EMR bleeds.

混合型APC结肠EMR,一种减少局部复发的新方法
背景和目的内镜下粘膜切除术(EMR)已成为切除大结肠息肉的标准方法,但使用标准技术有10%-30%的复发率。资料显示病灶切除基底边缘烧灼治疗可提高复发率。我们研究了一种新技术,混合APC辅助EMR,它对边缘和基部进行烧灼治疗,以评估其对局部复发的影响。方法回顾2018年5月至2019年11月,由一名内镜医师随访6个月的所有2cm息肉的EMR,采用标准EMR和混合APC辅助EMR评估局部复发和不良事件。结果经EMR切除息肉59例48例,随访6个月,平均年龄66.1岁,其中女性占45%。混合APC辅助EMR切除息肉30例,标准EMR切除息肉29例。总体而言,h-APC组有0例(0%)息肉局部复发,而标准组有6例(20.7%)息肉组织学证实局部复发(P = 0.01)。术后出血6例,hAPC组2例,标准组4例(P = 0.41)。结论在这项回顾性的前期研究中,混合APC辅助EMR治疗大结肠息肉切除后局部复发优于传统EMR,且EMR术后出血倾向较少。
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来源期刊
CiteScore
2.10
自引率
50.00%
发文量
60
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