Optically Controlled Drug Delivery System based on Porous Silicon and Microneedles patch

Abstract

Microneedles have been widely applied in biomedicine as tool both in diagnostics and therapeutics. In fact, microneedles are the perfect and painless interface between the derma and a device. Using microneedles as interface and a porous Silicon membrane as reservoir and optical controller, it is possible to realize a smart device for drug delivery. In this paper, we present the fabrication and the results for a patch device loaded with fluorescein molecules, as proof of concept.