Seroprevalence of Toxoplasma and Rubella in childbearing age women

Abant Medical Journal Pub Date : 1900-01-01 DOI:10.5505/ABANTMEDJ.2015.18189

M. Iraz, B. Gultepe, Aysenur Ceylan, M. Doymaz

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引用次数: 1

Abstract

Ozet Abstract Amac: Bu calismanin amaci, iki yillik donemde dogurgan yastaki kadinlarda konjenital enfeksiyonlara yol acabilme potansiyeline sahip Toksoplazma gondii ve Rubella virusune karsi olusan antikorlarin seroprevalansini arastirmakti. Yontem: Bu calismaya 01.01.2012 01.01.2014 tarihleri arasinda hastanemize basvuran dogurgan yastaki kadinlar dahil edildi. Hasta serumlarindaki Toksoplazma ve Rubella antikorlari VIDAS (BioMerieux, France) kitleri kullanarak enzim immunoassay (EIA) yontemiyle olculdu. Test sonuclari retrospektif olarak degerlendirildi. Bulgular: Rubella IgM antikorlarinda (n=15) %0.5 oraninda pozitiflik saptanirken, IgG antikorlarinda (n=451) %95.8 oraninda bulunmustur. Toksoplazma IgM antikorlarinda (n=38) %1.2 oraninda pozitiflik saptanirken, IgG antikorlarinda (n=158) bu oran %35.5 olarak belirlenmistir. Sonuc: Bolgemizde dogurgan cagdaki kadinlarda saptanan yuksek toksoplazma seronegatifliginden dolayi toksoplazma icin rutin taramaya ihtiyac bulunmaktadir. Ancak tum duyarli kadinlarin toksoplazma enfeksiyonlarindan korunma ve kontrolu acisindan egitimi konjenital enfeksiyon riskini azaltabilir. Saptadigimiz rubella seropozitiflik oranlarinin yuksek olmasi nedeniyle rubella icin rutin taramanin mutlak ihtiyac olmadigini dusunmekteyiz. Objective: The aim of this study was to investigate seroprevalence of antibodies against Rubella virus and Toxoplasma gondii, which may cause congenital infections in childbearing age women in a period of two years. Method: This study included pregnant and childbearing age women who had admitted to our hospital in the period between 01.01.2012 and 01.01.2014. Toxoplasma and Rubella antibodies tests in sera of patients were tested with an enzyme immunoassay (EIA) method using VIDAS (BioMerieux, France) kits. Test results were evaluated retrospectively. Results: Rubella IgM antibodies (n = 15) were detected as positive in 0.5% of samples and the IgG antibody seropositivity rate (n = 451) was found to be 95.8%. The Toxoplasma IgM antibody positivity rate was 1.2% (n= 38) and the IgG seropositivity was 35.5% (n = 158). Conclusion: Routine screening for toxoplasma seropositivity may be needed due to high seronegativity in among women of childbearing age in our region. Additionally, education of all susceptible women about protection and control of toxoplasma infection might be useful in decreasing the risk of congenital infections. However, routine screening for Rubella is considered unnecessary due to the high seropositivity rate.

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育龄妇女弓形虫和风疹的血清患病率

Ozet Abstract Amac：通过研究发现，先天性先天性脑瘫和风疹病毒血清抗体阳性率较高。日期：2011 年 1 月 1 日2012 年 1 月 1 日-2014 年 1 月 1 日的数据显示，该年龄段的儿童血清阳性率较高。血清中的Toksoplazma和Rubella抗原VIDAS（法国BioMerieux公司）试剂盒可用于免疫测定（EIA）。测试结果可追溯。参考文献风疹 IgM 抗原（n=15）为 0.5%，IgG 抗原（n=451）为 95.8%。IgM 抗核抗体（38 人）的比例为 1.2%，IgG 抗核抗体（158 人）的比例为 35.5%。研究结果：该研究发现了一种新的抗血清素抗体，其抗血清素抗体的比例为 35.5%。此外，风疹病毒还可能导致先天性畸形的风险。风疹血清检验或风疹病毒检测结果显示，儿童患风疹的风险较高。研究目的本研究旨在调查育龄妇女两年内风疹病毒和弓形虫抗体的血清流行率，这些病毒和弓形虫可能会导致先天性感染。研究方法研究对象包括 2012 年 1 月 1 日至 2014 年 1 月 1 日期间在我院住院的孕妇和育龄妇女。患者血清中的弓形虫和风疹抗体检测采用酶免疫分析法（EIA），使用 VIDAS（法国生物梅里埃公司）试剂盒。对检测结果进行了回顾性评估。结果在 0.5% 的样本中检测到风疹 IgM 抗体阳性（n = 15），IgG 抗体血清阳性率（n = 451）为 95.8%。弓形虫 IgM 抗体阳性率为 1.2%（n=38），IgG 血清阳性率为 35.5%（n=158）。结论由于本地区育龄妇女的血清阴性率较高，因此可能需要对弓形虫血清阳性进行常规筛查。此外，对所有易感妇女进行保护和控制弓形虫感染的教育可能有助于降低先天性感染的风险。然而，由于血清阳性率较高，我们认为没有必要对风疹进行常规筛查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Abant Medical Journal

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