Review on the Major Challenges and Difficulties of Farm Animal Cloning

T. Tadesse
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Abstract

Developments in biotechnologywould provide many new opportunities for livestock agriculture, human medicine, and animal conservation. Nuclear cloning involves the production of animals that are genetically identical to the donor cells used in a technique known as nuclear transfer. However, at present it is an inefficient process in farm animal and small number of the embryos transferred to the reproductive tracts of recipient mother result in healthy, long-term surviving clones. Recent cloning research also reveals high failure rates, premature deaths, and dysfunctioning of internal organs.Food products from healthy clones, i.e. meat or milk, did not differ from products from healthy conventionally bred animals.  Even though the food products of cloned animals showed no differences with conventional offspring or products,throughout the world there is significant public opposition to the introduction of meat and milk from cloned animals and their progeny into the food supply. Cloning also threatens the welfare of surrogate mothers, the underlying health of the animals and the next generation, the consequential effect on food safety are critical aspects that require investigation to gain regulatory and consumer acceptance.Data on clones of farmed species for food production other than cattle and pigs have remained limited and do not allow for assessment of food safety or animal health and welfare aspects. Keywords: Biotechnology, Cloning, Food safety, Nuclear transfer, Trans generational effects,
农业动物克隆的主要挑战和困难综述
生物技术的发展将为畜牧业、人类医学和动物保护提供许多新的机会。核克隆是指在核移植技术中培育出与供体细胞基因完全相同的动物。然而,目前在农场动物中,这是一个效率低下的过程,很少有胚胎移植到受体母亲的生殖道,产生健康、长期存活的克隆。最近的克隆研究也揭示了高失败率、过早死亡和内部器官功能障碍。来自健康克隆动物的食品,即肉或奶,与来自健康传统饲养动物的产品没有区别。尽管克隆动物的食品与传统的后代或产品没有区别,但在世界各地,公众反对将克隆动物及其后代的肉和奶引入食品供应。克隆还威胁到代孕母亲的福利,动物和下一代的潜在健康,以及对食品安全的影响,这些都是需要调查的关键方面,以获得监管机构和消费者的接受。关于牛和猪以外用于粮食生产的养殖物种的克隆数据仍然有限,无法评估食品安全或动物健康和福利方面的情况。关键词:生物技术,克隆,食品安全,核转移,跨代效应
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