Successful treatment of type ii diabetes mellitus with infected diabetic foot ulcer caused by ESBL producing Klebsiella pneumonia with cefepime plus sulbactam (Supime): A case report

Vijay Shankar Upadhyay, Ayush Upadhayay
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Abstract

Diabetic patients are at significant risk of developing neuropathy, leading to a diabetic foot injury. Complications of diabetic foot injury may lead to gangrene and non-traumatic lower extremity amputations. Diabetic patients with diabetic foot ulcers are more prone to bacterial infections and are associated with high chances of amputation. The diabetic patient flora provides an ideal environment for Gram-positive and Gram-negative bacterial growth, leading to increased morbidity and mortality. The antimicrobial-resistant Gram-negative bacterial infections in diabetic patients have a higher probability of amputation. Here we discuss a case of a 70-year male diabetic patient successfully treated with Supime (cefepime plus sulbactam) who had undergone an amputation of the right great toe and infected left foot ulcer due to ESBL producing K. Pneumonia.
头孢吡肟加舒巴坦治疗2型糖尿病合并ESBL产肺炎克雷伯菌所致的糖尿病足溃疡1例
糖尿病患者发生神经病变的风险很大,从而导致糖尿病足损伤。糖尿病足损伤的并发症可能导致坏疽和非创伤性下肢截肢。患有糖尿病足溃疡的糖尿病患者更容易发生细菌感染,并且截肢的几率很高。糖尿病患者的菌群为革兰氏阳性和革兰氏阴性细菌的生长提供了理想的环境,导致发病率和死亡率的增加。糖尿病患者中耐药革兰氏阴性菌感染有较高的截肢概率。在这里,我们讨论一个70岁的男性糖尿病患者,他成功地用舒吡肟(头孢吡肟加舒巴坦)治疗了右大脚趾,由于ESBL产生肺炎克雷伯菌而感染了左脚溃疡。
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