Successful treatment of type ii diabetes mellitus with infected diabetic foot ulcer caused by ESBL producing Klebsiella pneumonia with cefepime plus sulbactam (Supime): A case report
{"title":"Successful treatment of type ii diabetes mellitus with infected diabetic foot ulcer caused by ESBL producing Klebsiella pneumonia with cefepime plus sulbactam (Supime): A case report","authors":"Vijay Shankar Upadhyay, Ayush Upadhayay","doi":"10.53346/wjbpr.2022.2.2.0024","DOIUrl":null,"url":null,"abstract":"Diabetic patients are at significant risk of developing neuropathy, leading to a diabetic foot injury. Complications of diabetic foot injury may lead to gangrene and non-traumatic lower extremity amputations. Diabetic patients with diabetic foot ulcers are more prone to bacterial infections and are associated with high chances of amputation. The diabetic patient flora provides an ideal environment for Gram-positive and Gram-negative bacterial growth, leading to increased morbidity and mortality. The antimicrobial-resistant Gram-negative bacterial infections in diabetic patients have a higher probability of amputation. Here we discuss a case of a 70-year male diabetic patient successfully treated with Supime (cefepime plus sulbactam) who had undergone an amputation of the right great toe and infected left foot ulcer due to ESBL producing K. Pneumonia.","PeriodicalId":267430,"journal":{"name":"World Journal of Biological and Pharmaceutical Research","volume":"35 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Biological and Pharmaceutical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53346/wjbpr.2022.2.2.0024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Diabetic patients are at significant risk of developing neuropathy, leading to a diabetic foot injury. Complications of diabetic foot injury may lead to gangrene and non-traumatic lower extremity amputations. Diabetic patients with diabetic foot ulcers are more prone to bacterial infections and are associated with high chances of amputation. The diabetic patient flora provides an ideal environment for Gram-positive and Gram-negative bacterial growth, leading to increased morbidity and mortality. The antimicrobial-resistant Gram-negative bacterial infections in diabetic patients have a higher probability of amputation. Here we discuss a case of a 70-year male diabetic patient successfully treated with Supime (cefepime plus sulbactam) who had undergone an amputation of the right great toe and infected left foot ulcer due to ESBL producing K. Pneumonia.