The Surgical Management of Primary Hyperparathyroidism: The Experience in Tikur Anbessa Specialized Tertiary Referral and Teaching Hospital, Addis Ababa, Ethiopia

S. Wondimu, B. Nega
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Abstract

Primary hyperparathyroidism is an endocrine disorder characterized by excessive and inappropriate release of Parathormone (PTH) from parathyroid glands resulting in diverse clinical manifestations involving the skeletal system in the form of bone and joint pains and pathological fractures, the gastrointestinal system in the form of dyspepsia from Peptic ulcer disease and pancreatitis, nephrolithiasis and other neuropsychiatric and nonspecific symptoms. There is nothing known about the epidemiology of this condition in our country and experience in Parathyroidectomy is very limited. In the biggest tertiary referral and teaching hospital in the country, only seven cases have been seen and treated over a period of seven years from 2007-2014 and only three had complete medical documents. We therefore present these three cases in detail and review the available literature in the management of primary hyperparathyroidism. Key words : Primary hyperparathyroidism, hungry bone disease, parathyroid adenoma
原发性甲状旁腺功能亢进的外科治疗:提库尔Anbessa专科三级转诊和教学医院的经验,亚的斯亚贝巴,埃塞俄比亚
原发性甲状旁腺功能亢进是一种以甲状旁腺分泌甲状旁腺激素(PTH)过量和不适当释放为特征的内分泌紊乱,其临床表现多样,包括骨骼系统,表现为骨、关节疼痛和病理性骨折,胃肠道系统,表现为消化性溃疡疾病和胰腺炎、肾结石等神经精神和非特异性症状。我国对该病的流行病学尚不清楚,甲状旁腺切除术的经验也非常有限。在该国最大的三级转诊和教学医院,在2007-2014年的7年期间,只有7个病例得到了诊治,只有3个病例有完整的医疗文件。因此,我们详细介绍了这三个病例,并回顾了原发性甲状旁腺功能亢进的治疗文献。关键词:原发性甲状旁腺功能亢进,饥饿骨病,甲状旁腺瘤
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