A Novel Portable Nanotechnology Approach For Targeted Cancer Therapy

U. Bunyatova, C. Koçum, E. Haberal, Alaskar Asadullayev, Gulbala Salamov
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Abstract

Several health-related problems can be monitored, treated and minimized with the use of technological equipment and treatment methods. The development of new synthesis methods and designing nanostructured biosensing colloidal polymeric bioorganic nanomaterials and metal using cheap and environmentally friendly methods remains a challenge to the scientific community. This study is focused on the presentation a new approaches to targeted treatment with a novel portable sensing system. We have found that aqueous blend of intercalated polysaccharides nanocomposites with a reactive functionalizing copolymer and silver nanoparticules (AgNP-s) are sensitive towards a visible light source- white light emitted diode (wLED). The presented system and ideas can be used as an integrated pathways for targeted cancer therapy, biosensors, and drug delivery systems. AgNP-s, having unique sizes in the range between 2 −6 nm have been obtained by the influence of harmless wLED treatment during extremely short time around 10–12 minutes. wLED based portable wire-device is an effective route to obtain bio-nanocomposition with anticancer and drug delivery potential as a pathway of targeted cancer therapy. Moreover, after applying multifunctional biocomposition on the tumor area this effective, eco-friendly, low cost and harmless for human health treatment takes only 10–12 minutes.
一种新的便携式纳米技术用于靶向癌症治疗
利用技术设备和治疗方法,可以监测、治疗和尽量减少若干与健康有关的问题。开发新的合成方法和设计纳米结构的生物传感胶体聚合物和生物有机纳米金属材料仍然是科学界面临的挑战。本研究的重点是介绍一种新的便携式传感系统的靶向治疗的新方法。我们发现,含有活性功能化共聚物的插层多糖纳米复合材料与纳米银粒子(AgNP-s)的水共混物对可见光源白光发射二极管(wLED)敏感。所提出的系统和思想可以作为靶向癌症治疗、生物传感器和药物输送系统的综合途径。通过无害化的wLED处理,在极短的时间内(约10-12分钟)获得了尺寸在2 - 6 nm范围内的AgNP-s。基于wLED的便携式线器件是获得具有抗癌和药物传递潜力的生物纳米组合物的有效途径,是肿瘤靶向治疗的一个途径。此外,将多功能生物组合物涂抹在肿瘤部位后,这种对人体健康有效、环保、低成本、无害的治疗仅需10-12分钟。
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